Less than 0.7
Between 0.7 and 0.9
Between 0.9 and 1.1
Between 1.1 and 1.3
Greater than 1.3
Unavailable
Note: Detailed model scenario descriptions can be found below the graph or on the Technical Notes tab.
Note: Starting on July 19, 2023, this page updates on a bi-weekly schedule to align with the cadence of CDC Nowcast updates.
LEMMA is an open-source SEIR model with compartments for hospitalization and symptom severity. The model is calibrated to hospitalization, ICU and death data using Bayesian methods. LEMMA provides credibility intervals and scenarios for future cases, hospitalization, ICU, deaths and Rt. Users can download the LEMMA package and input their own data and priors for parameters using R or a simple Excel interface.
Covidestim calculates state-level effective reproductive numbers, taking cases, deaths and test positivity rates as inputs. It has corrections to account for lags in diagnosis, disease duration and mortality risk.
Code repositoryThis Rt-estim-gamma model by Isaac Goldstein and Volodymyr Minin at UC Irvine and Jon Wakefield at University of Washington is a branching process inspired model where cases are modeled as noisy realizations of latent unobserved incidence. The number of diagnostic tests is incorporated as a covariate into the surveillance model to adjust for changes in testing volume over time.
Code RepositoryThis model by Isaac Goldstein and Volodymyr Minin at UC Irvine uses a modified compartmental model where viral pathogen genome concentrations are modeled as a noisy realization of a weighted sum of the number of infectious and recently recovered individuals.
Code RepositoryThe UCSF model uses raw data from three sources: new cases by county from California Health and Human Services; wastewater readings from the Cal-SuWers network (“Wastewater (C)”), BioBot Analytics (“Wastewater (B)”) and WastewaterScan (“Wastewater (W)”). The Wallinga-Teunis technique is used to estimate reproduction numbers, corrected for right censoring of the case detection data.
Raw databs = 'ad'
in mgcv
's gam()
function) to the normalized wastewater data to remove noise and recover the underlying trend of interest-- log-transformed input data undergoes smoothing using a TOBIT (censored normal) error distribution; dates with concentrations of 0 are treated as non-detects with censored outcomes, and the limit of detection is initially estimated using the lowest nonzero value in recent data. Smooth fits are used to detect outliers, i.e., observations with extreme residuals and thus unlikely to be in 95% of time series generated under the smooth model. Any outliers so flagged are resampled. Then the wastewater concentrations are converted into an estimated time series of infection events by deconvolving the smoothed wastewater signal with an estimate of the shedding load distribution. For deconvolution, following Huisman’s initial approach is used (available through estimateR
's deconvolve_incidence()
function) with a gamma-distributed incubation period with mean 3.58 days and SD 1.77 days, combined with a fecal shedding load distribution from the systematic review of Benefield et al., gamma distributed with mean 6.7 days and SD 7 days. Once the time series of infection events has been estimated, Rt is recovered based on an estimate of the generation interval distribution using standard renewal equation methods with the default priors for Rt in EpiEstim to have an expected value of 1. Rt estimates for each sewershed are converted to the overall county estimate using a population-weighted average. Inference is then conducted by calculating bootstrap quantiles and odds of agreement of epidemic trajectory with the point estimate based on original data. Wastewater samples are collected and processed by WastewaterSCAN, an organization that partners with the Cal-SuWers Network to monitor wastewater at wastewater treatment plants in California. To reduce the effect of noise, the wastewater data is processed with spline smoothing followed by a square root transformation. To convert from viral shedding events in wastewater to a time series of infection events, the estimateR method uses a gamma delay distribution with a mean of 5 days and a standard deviation of 0.5 days (Huisman et al. 2022). Using the inferred infection time series, estimateR calculates the effective reproduction number by implementing a wrapper around the EpiEstim package (Scire et al. 2022). The generation time distribution input to EpiEstim is gamma distributed with a mean of 6.84 days, and a standard deviation of 4.48 days (Manica et al. 2022).
To account for lags introduced by deconvolution and wastewater data reporting, wastewater for each treatment plant is forecasted until the present day using a TBATS time series model (T: Trigonometric seasonality, B: Box-Cox transformation, A: ARIMA errors, T: Trend, S: Seasonal components) optimized by the forecast package. TBATS is an exponential smoothing model designed to forecast data with complex seasonal patterns (De Livera et al. 2011). This step provides a nowcasted, current-day estimate of the effective reproduction number. The effective reproduction number for each wastewater treatment plant is subsequently aggregated to the county level via population weighting.
CDC overview of wastewater surveillanceStatewide hospitalization data from the National Healthcare Safety Network (NHSN) is processed with locally estimated scatterplot smoothing (LOESS). Two delay distributions are then used to deconvolve from observed hospital admissions to inferred infections: (1) an estimate of the incubation period, based on Aguila-Mejia et al. (2022) and (2) the delay from symptom onset to hospital admission, based on the California COVID-19 case registry. Based on this inferred infection time series and a generation time distribution, estimateR calculates the effective reproduction number. The generation time distribution is given by a gamma distribution with a mean of 6.84 days and a standard deviation of 4.48 days (based on Manica, De Bellis & Guzzetta et al. 2022).
To account for lags introduced by deconvolution and NHSN data reporting, hospitalizations are forecasted until the present day prior to estimation of the effective reproduction number. Forecasting is executed using a TBATS time series model (T: Trigonometric seasonality, B: Box-Cox transformation, A: ARIMA errors, T: Trend, S: Seasonal components) optimized by the forecast package (De Livera, Hyndman & Snyder et al. 2011).
The Global Epidemic and Mobility Model (GLEAM) uses a individual-based, stochastic spatial epidemic model. The model uses mobility data and travel patterns to simulate spatial contact patterns. The likely ranges of basic parameters, such as R0 and IFR, are inferred from observed data.
Raw dataThe Reich Lab at the UMass-Amherst is an Influenza Forecasting Center of Excellence and the source for the official CDC COVID-19 Forecasting page. Taking other forecasts as the input, this is arithmetic average across eligible models of cumulative deaths forecasts. Forecasts are weekly out to four (4) weeks, at the state and national level.
Raw dataLEMMA is an open-source SEIR model with compartments for hospitalization and symptom severity. The model is calibrated to hospitalization, ICU and death data using Bayesian methods. LEMMA provides credibility intervals and scenarios for future cases, hospitalization, ICU, deaths and Rt. Users can download the LEMMA package and input their own data and priors for parameters using R or a simple Excel interface.
This model by Vladimir Minin and Damon Bayer at UC Irvine is a SEIR type model stratified by Omicron vs non-Omicron infection with hospitalization compartments. The model is calibrated to California hospital data from the California open data portal using data on COVID variant prevalence from GISAID."
Raw dataCovidNearTerm is a bootstrap-based method based on an autoregressive model to estimate at the county level the expected number of COVID-19 patients that will hospitalized 2-4 weeks into the future. It is based on the work of researchers at UCSF (Adam Olshen), Stanford (Kristopher Kapphahn, Ariadna Garcia, Isabel Wang and Manisha Desai) and Memorial Sloan-Kettering (Mithat Gonen).
Raw dataModel forecasts are the result of utilizing the forecast package's automatic ARIMA forecasting model. Note that the form of the model may vary between counties and over subsequent published forecasts.
Modeling methodsThe Holt's linear trend method extends simple exponential smoothing to allow the forecasting of data with a trend (Holt 2004).
The Damped Holt's model is an exponential smoothing model designed to damp erratic trends (Gardner & Mckenzie 1985).
The neural network autoregression (NNETAR) model is a system of feed-forward neural networks with a single hidden layer and lagged inputs.
No booster scenario assumes no future recommendation to get additional booster doses or receive additional vaccination.
High-risk booster scenario assumes that the uptake of annual reformulated booster in high-risk groups (65+ and other individuals with underlying risk factors for severe COVID-19 outcomes) follows uptake observed for the booster dose during the 2023-24 season and negligible vaccination among others outside of high-risk groups.
All booster scenario that the uptake of annual reformulated booster in all groups follows uptake observed for the booster dose during the 2023-24 season.
Low immune escape scenario assumes immune escape occurs at a constant rate of 20% per year.
High immune escape scenario assumes immune escape occurs at a constant rate of 50% per year.
LEMMA provides scenarios to depict how Omicron might affect hospitalizations in California in the coming weeks and months.
Optimistic assumes the Omicron hospitalization rate in immunonaive is much lower than for Delta and length of stay is shorter than for Delta.
Central assumes the Omicron hospitalization rate in immunonaive is lower than for Delta.
Pessimistic assumes the Omicron hospitalization rate in immunonaive is slightly lower than for Delta and booster vaccine effectiveness is lower,.
LEMMA scenarios either include 'for COVID' only (no incidental COVID) or 'with COVID' (includes incidental COVID). The current model assumption is that 40% of COVID positive patients are incidental admissions (not primarily due to COVID).
LEMMA is an open-source SEIR model with compartments for hospitalization and symptom severity. The model is calibrated to hospitalization, ICU and death data using Bayesian methods. LEMMA provides credibility intervals and scenarios for future cases, hospitalization, ICU, deaths and Rt. Users can download the LEMMA package and input their own data and priors for parameters using R or a simple Excel interface.
Raw data
The Shaman group from Columbia University projects nationwide, county-level estimates of R-effective, daily new confirmed case, daily new infection (both reported and unreported), cumulative demand of hospital beds, ICU, and ventilators, as well as daily mortality (2.5, 25, 50, 75 and 97.5 percentiles).
No change assumes that current contact rates will remain unchanged in the future.
1x increased transmission (5_1xbeta_Lmin0p5) assumes a one-time 5% increase in contact rates at the start of the projection. The following week, the effective reproduction number R is set to 1. As the simulation progresses, R_eff decreases as the fraction of susceptible individuals in the population decreases.
Raw dataModels based on previously observed variant proportions are used to generate real-time estimates of variant proportions. Each model is applied separately to both the integrated genomic epidemiology dataset (IGED) and Terra.
The logistic proportion model is based on methods presented in Althaus et al 2021. It uses the last 60 days of data to estimate a trend in variant growth assuming it is following a logistic pattern.
The multinomial spline model is based on methods presented in Davies et al 2021. It uses a multinomial logistic regression with cubic spline terms to estimate temporal trends in the frequency each variant is observed.
The variant simple growth model is currently only estimated statewide and uses variants specific effective reproduction numbers (Reff) and simple growth models to estimate variant specific case counts. Variant proportions are then estimated from these case counts as the proportion of projected new cases caused by each variant. The model to estimate variant specific reproduction numbers is based on methods presented in Figgins & Bedford 2021.
The ensemble mean model is the average of the available projection models listed above. The range displayed in the plot is the lowest to highest uncertainty estimates from the input models.
A basic quantile autoregression fit using influenza-related hospitalizations and doctors visits, jointly trained across locations using the most recently available 21 days of data.
Deterministic fit of a compartmental SIHR model to weekly, CA region level, hospitalization incidence profiles, followed by stochastic simulations using the inferred parameter distributions. The ‘H’ compartment is divided into two compartments to ensure the correct generation time for the Infectious compartment and proper fitting of the portion of infectious individuals that are hospitalized. For each of the five CA regions, the model fit is inferred by an MCMC procedure and run forward at a weekly cadence.
Random forest ensemble of the predictors generated from the SGroup-SIkJalpha submission, HHS data, as well as historical FluSurv-NET data.
Equally weighted ensemble of simple time-series baseline models. Each baseline model calculates first differences of incidence in recent weeks. These differences are sampled and then added to the most recently observed incidence.
The CDC Ensemble from the CDC FluSight Challenge includes all available flu forecasts for the state of California.
These forecasts consist of four time series forecast approaches:
The subtype H3N2 dominant scenarios assume that the next season is dominated by influenza A/H3N2, indexed on the age dynamics and severity based on the 2017-2018 season.
The subtype H1N1 dominant scenarios assume that the next season is dominated by influenza A/H1N1, indexed on the age dynamics and severity based on the 2019-2020 season.
The high vaccine coverage scenarios assume that the vaccine coverage is 20% higher than in the 2022-2023 flu season in all age groups and jurisdictions.
The medium vaccine coverage scenarios assume that the vaccine coverage is same as in the 2022-2023 flu season in all age groups and jurisdictions. Overall US coverage is about 49% in this scenario.
The low vaccine coverage scenarios assume that the vaccine coverage is 20% lower than in the 2022-2023 flu season in all age groups and jurisdictions.